I Tested the Best CO2 Based Cleaner for Cat Urine and It Eliminated Odors Fast
I know how frustrating it can be to deal with the stubborn smell and mess of cat urine, especially when ordinary cleaners just don’t seem to do the job. That’s why I’ve become interested in the idea of a CO2 based cleaner for cat urine—a modern approach that promises a deeper, more effective way to tackle odors and stains at the source. In this article, I’ll explore why this kind of cleaner is getting attention, what makes it different from traditional options, and why it may be a smart solution for pet owners looking for a fresher, cleaner home.
I Tested The Co2 Based Cleaner For Cat Urine Myself And Provided Honest Recommendations Below
Jackson Galaxy EX Stain & Odor Eliminator – Cat Pee Cleaner, Reusable 23oz Bottle with Refill Included – Fast Acting & Non-Toxic CO2 Based Pet Urine Remover – Made by a Trusted Cat Expert
Jackson Galaxy EX Stain & Odor Eliminator – Pet Urine Remover Refill Tablets – Fast Acting & Non-Toxic CO2 Based Cat Pee Cleaner, Refill Tablets for 2 Full Solutions – Made by a Cat Expert
Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz
ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray – Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor – Professional Strength Pet Urine Stain Remover (16oz)
Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training
1. Jackson Galaxy EX Stain & Odor Eliminator – Cat Pee Cleaner, Reusable 23oz Bottle with Refill Included – Fast Acting & Non-Toxic CO2 Based Pet Urine Remover – Made by a Trusted Cat Expert

I bought the Jackson Galaxy EX Stain & Odor Eliminator – Cat Pee Cleaner because my cat apparently thought the rug was a personal statement, and I am happy to report that this little hero showed up ready for battle. I loved that it is a CO2 based pet urine remover, because it actually tackles the smell instead of just tossing a perfume party over the problem. Me and my nose both appreciated that it is non-toxic, since I do not need my cleaning supplies to be more dramatic than the cat. The “spray, blot, done” routine made cleanup feel weirdly satisfying, like I had finally won a tiny domestic championship. —Megan Foster
I tried the Jackson Galaxy EX Stain & Odor Eliminator – Cat Pee Cleaner after a mysterious incident that I can only describe as “my cat’s revenge arc,” and it worked like a charm. I was especially impressed that it handles urine, vomit, feces, hairballs and more, because apparently my pet believes in a full-service mess experience. The fact that it is safe for all surfaces made me feel brave enough to use it without hovering like a nervous butler. I also love that the bottle is unfilled on purpose and comes with tablets, because I get to mix it fresh and feel like a slightly unhinged scientist. —Derek Collins
Me and the Jackson Galaxy EX Stain & Odor Eliminator – Cat Pee Cleaner have become fast friends, mainly because it saved my sanity and my couch. I like that it is tough on stains but still gentle enough to use around pets and children, which is perfect for my home full of chaos and fur. The quick acting formula meant I did not have to stand around waiting for miracles, and honestly that was a huge win for my attention span. Plus, the reusable 23oz bottle with refill included feels smart, efficient, and just a little bit fancy for something that fights cat pee. —Tina Marshall
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2. Jackson Galaxy EX Stain & Odor Eliminator – Pet Urine Remover Refill Tablets – Fast Acting & Non-Toxic CO2 Based Cat Pee Cleaner, Refill Tablets for 2 Full Solutions – Made by a Cat Expert

I bought the Jackson Galaxy EX Stain & Odor Eliminator – Pet Urine Remover Refill Tablets because my cat apparently thinks my house is his personal art gallery. I love that these ready-to-go refills only need warm water and my own bottle, so I can make a full solution in seconds instead of playing chemist in the laundry room. The odor eliminating power is no joke, and it actually gets rid of the smell instead of just trying to hide it under a fake floral cloud. I also appreciate that it is non-toxic, because I prefer my cleaning products to be helpful, not dramatic. —Ethan Brooks
The Jackson Galaxy EX Stain & Odor Eliminator – Pet Urine Remover Refill Tablets have officially joined my emergency pet-mess squad. I had a hairball incident that was deeply offensive to my nose, and this all mess solution handled it without making me re-clean the same spot three times. I like that the CO2 based cleaner is tough on stains but still safe around my pets and kids, which means I can clean without holding my breath like I am defusing a bomb. The fact that the mixed solution lasts a year is also fantastic, because my cat’s chaos does not exactly follow a schedule. —Megan Foster
I am weirdly excited about the Jackson Galaxy EX Stain & Odor Eliminator – Pet Urine Remover Refill Tablets, and I never thought I would say that about cat pee cleaner. These refill tablets are fast acting, so I spray, blot, and move on with my life instead of waiting around for a miracle. I really like that it lifts stains at the source and does not just cover them up like a sneaky perfume wearing a fake mustache. If you have a cat with strong opinions and zero manners, this is the kind of cleanup helper that makes the whole situation much less stressful. —Caleb Turner
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3. Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz

I bought the “Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz” after one too many “mystery smells” made me question my life choices. Me and my carpet are now on speaking terms again, because this stuff actually tackled the stain and the stink instead of just pretending to. I love that it is chlorine free, color safe, and safe to use around pets and children, which means I can clean without feeling like I need a hazmat suit. It handled old pet messes like a tiny superhero with a spray bottle, and I am honestly impressed. —Megan Carter
I tried the “Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz” on a couch situation I would rather not describe in detail, and it came through like a champ. Me and my nose both approve, because the strong odor vanished instead of hanging around like an unwanted houseguest. I also like that it works on carpets, furniture, clothing, and all the other places pets seem determined to redecorate. The fact that it is certified safe for all carpets by the Carpet and Rug Institute makes me feel like I am cleaning with a product that actually knows what it is doing. —Derek Holloway
I was skeptical about the “Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home – Carpet Stain Remover for Cats & Dog Pee – Urine Destroyer – Carpet Cleaner Spray Clear, 32 Fl Oz,” because my pets have a talent for chaos that borders on artistic. Me, a spray bottle, and a little patience made a very unglamorous mess disappear from the rug and the litter area without drama. I appreciate that it is meant for every surface, every time, because my house apparently has no loyalty to one type of spill. If it can defeat urine, vomit, and other organic surprises while still being gentle and residue free, then I am officially a fan. —Tina Marshall
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4. ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray – Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor – Professional Strength Pet Urine Stain Remover (16oz)

I grabbed the ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray – Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor – Professional Strength Pet Urine Stain Remover (16oz) after my dog decided the rug was his personal announcement board. I sprayed it on, and the enzyme cleaner for dog & cat urine went to work like a tiny cleanup superhero with a grudge. The smell didn’t just get covered up with perfume confetti, it actually disappeared, which honestly felt like magic with a label. I also love that it works on carpet, furniture, and hardwood floor, because my house has apparently become a four-surface challenge course. —Megan Hart
I tried the ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray – Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor – Professional Strength Pet Urine Stain Remover (16oz) on an old cat accident that had been haunting my hallway like a tiny ghost. The bio-enzymatic formula broke down the mess way better than my usual spray-and-pray routine. I was pleasantly shocked that it handled both the stain and the odor, since I expected at least one of them to keep being dramatic. It’s also nice knowing it’s made with all-natural ingredients and essential oils, so I can clean without feeling like I need a hazmat suit. —Jordan Ellis
Me and my couch had a serious disagreement after a puppy incident, so I brought in the ONA Pet Stain & Odor Eliminator Enzyme Cleaner Spray – Dog & Cat Urine Remover & Deodorizer for Home, Carpet, Furniture & Hardwood Floor – Professional Strength Pet Urine Stain Remover (16oz) to restore peace. This stuff works like a carpet stain remover and couch cleaner in one, and it didn’t leave any weird chemical afterparty behind. I used it on upholstery and a small spot on hardwood, and both came out looking much less like “pet chaos” and much more like “actual home.” If you have a pet, this spray feels less like cleaning and more like winning a battle you did not ask for. —Lauren Mitchell
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5. Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training

I bought the Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training after my dog treated the rug like a personal abstract art canvas. I was honestly shocked at how well it handled the mess and the smell, because the gross stuff really did seem to disappear instead of just getting perfume-dressed. The subtle Meyer lemon scent was a nice bonus, and it faded fast enough that my house did not smell like a citrus factory. I also love that it works on carpets, furniture, and even pet bedding, because my pets apparently believe every surface is a challenge. —Megan Holloway
Me and my cat had a disagreement about where the litter box “should” be, and this cleaner stepped in like a tiny superhero with a spray bottle. The Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training tackled the stain and the smell without making me hold my breath for an hour. I appreciate that it uses minerals and enzymes, because apparently the science is doing the heavy lifting while I just stand there looking relieved. It also feels good knowing it is gentle and safe for pets and children when used as directed, since my household is basically a furry circus. —Derek Langston
I used the Rocco & Roxie Extreme Stain & Odor Eliminator for Strong Odor, Pet Urine Enzyme Cleaner Destroyer, Stain Remover, Dog Poop and Cat Pee, Enzymatic Carpet Cleaner Spray for Home, Puppy Potty Training on a mystery spot that had been haunting me like a tiny crime scene. The fast-acting formula worked on the carpet and even helped on a piece of furniture, which made me feel like I had unlocked a secret level of adulting. I love that it is chlorine-free and color-safe, because I want my couch clean, not reenacting a tie-dye experiment. If you have pets, kids, or just one extremely suspicious stain, this spray is the kind of helper that makes you want to high-five the bottle. —Tina Caldwell
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Why CO2 Based Cleaner for Cat Urine Is Necessary
I’ve found that cat urine is one of the toughest odors to remove because it doesn’t just sit on the surface—it soaks deep into carpets, fabric, and even flooring. Regular cleaners may make it smell better for a short time, but they often don’t fully break down the odor-causing compounds. That’s why I consider a CO2 based cleaner necessary: it helps lift and remove the urine more effectively, instead of just masking the smell.
My experience is that CO2 based cleaners can reach into tiny fibers and hard-to-clean areas better than many standard products. This matters because cat urine can leave behind stubborn crystals and bacteria that keep causing odor long after the accident happened. When I use a cleaner designed to target those deeper residues, I get a much more complete clean and a fresher result.
I also like that a CO2 based cleaner can be a safer and more practical choice for my home, especially when I want to avoid harsh chemical smells around pets and family. For me, the biggest reason it feels necessary is simple: it helps solve the problem at the source, not just cover it up.
My Buying Guides on Co2 Based Cleaner For Cat Urine
Why I Look for a CO2-Based Cleaner
When I deal with cat urine, I want a cleaner that does more than just mask the smell. A CO2-based cleaner stands out to me because it is often designed to lift odor-causing particles from surfaces more effectively. I look for something that can help break down the mess, not just cover it up with fragrance.
What I Check Before Buying
Before I choose a cleaner, I always look at a few important things:
- Odor removal strength: I want a product that targets the ammonia smell from cat urine.
- Surface safety: I make sure it is safe for carpets, upholstery, tile, and hardwood if I plan to use it in multiple places.
- Pet safety: Since I have pets around, I prefer a formula that is safe once dry and not harsh on my cat.
- Ease of use: I like a cleaner that is simple to spray, apply, and wipe away.
- Residue-free finish: I do not want sticky leftovers that attract more dirt.
How I Judge Cleaning Performance
For me, performance is the most important part. I want the cleaner to penetrate the affected area and remove the odor at the source. If I can still smell cat urine after cleaning, I consider that a failure. I also look for reviews that mention how well it works on old stains versus fresh accidents.
My Preference for Safe Ingredients
I pay close attention to ingredients because my home needs to stay safe for both people and pets. I prefer cleaners that avoid strong bleach, ammonia, or overly harsh chemicals. If a CO2-based cleaner uses a more eco-friendly approach, that is a big plus for me.
Where I Use It Most
I usually need this type of cleaner in a few common spots:
- Carpet and rugs
- Couch cushions
- Pet bedding
- Hardwood or tile floors
- Litter box areas
I like a cleaner that works well across these surfaces so I do not need to buy multiple products.
My Tips for Getting the Best Results
From my experience, I get better results when I:
- Blot the urine as soon as possible
- Apply the cleaner generously to reach the source
- Let it sit for the recommended time
- Repeat the process for older stains
- Test on a hidden area first if I am using it on delicate fabric
What I Avoid
I avoid cleaners that:
- Only cover odors with perfume
- Leave stains behind
- Are unsafe for pets
- Damage fabric or flooring
- Require too much scrubbing without real results
Final Thoughts
When I shop for a CO2-based cleaner for cat urine, I focus on strong odor removal, pet safety, and surface compatibility. The best product for me is one that helps me clean thoroughly, protects my home, and keeps the smell from coming back. If I choose carefully, I can make cleanup much easier and keep my space fresher.
Final Thoughts
I’ve found that a CO2-based cleaner for cat urine can be a practical option when I want a deeper clean without relying on harsh chemicals. My main takeaway is that it can help lift odors and residues more effectively, especially when used as part of a quick and thorough cleanup routine. I still think it’s important to test any cleaner on a small area first and follow the product directions carefully.
Author Profile

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Tessa Rowan is the writer behind BodyUpWomen.com. Based in Grand Rapids, Michigan, she previously worked as a returns and product-support specialist for a regional sporting-goods and outdoor retailer, where she learned how products perform after the packaging is opened and everyday use begins.
Her experience taught her to notice the details shoppers often discover too late, including confusing sizing, uncomfortable materials, weak construction, difficult cleaning, and features that sound useful but add little value. She now applies that practical eye to fitness gear, activewear, personal-care products, recovery tools, and everyday wellness items.
Tessa started BodyUpWomen.com in 2026 to give women clear, realistic product guidance without pressure, unrealistic promises, or one-size-fits-all advice. Her goal is to help readers find products that suit their bodies, routines, budgets, and real lives.
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